Theoretical Analysis of the Extended Effect of Radiofrequency Thermal Ablation Process: A Case Study of Liver

M Emetere, B Muhammad, E Bolujo

Abstract


The success of the radiofrequency ablation (RFA) in treating liver has shown great success. Recently, greater successes are achieved however without its challenges. Possible side effects after ablation therapy include abdominal pain, infection in the liver, and bleeding into the chest cavity or abdomen. The mathematical expression for the conversion of sound to heat energy was used to investigate the conductive transference of heat energy from the ablation zone to the surrounding tissues. We considered two groups of probes and the maximum energy available for transfer. It was discovered that probing technique is capable of releasing heat energy of 120 J for each probe from each ablation zone. This omission is very critical for clinical processes. For above ten ablation zones, enormous transference of energy to the neighboring tissues is further enhanced by the differential tissue impedance. Hence, there is more danger when excess tissue impedance is imposed on the ablation zones.


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References


Solbiati, L., Ierace, T', Tonolini, M., Osti, V., and Cova, L., Radiofrequency thermal ablation of hepatic metastases. European journal of ultrasound, 13: 149-158, 2001. Crossref

Vick, B., and Ozisik, M. N., Growth and Decay of a Thermal Pulse Predicted by the Hyperbolic Heat Conduction Equation. Journal of Heat Transfer, 105: 902-7, 1983. Crossref

Shih, T. C., Kou, H. S., Liauh, C, T., and Lin, W. L., The impact of thermal wave characteristics on thermal dose distribution during thermal therapy: a numerical study Med. Phys., 32: 3029-36. Crossref

Hammerich, D., Wright, A.W., Mahvi, D. M., Lee, Jr F.T., and Webster, J.G., Hepatic bipolar radiofrequency ablation creates coagulation zones close to blood vessels: a finite element study. Medical & biological engineering & computing, 41: 317-323, 2003. Crossref

Lu, D., Raman, S., Vodopich, D., Wang, M., Sayre, J., and Lassman, C., Effect of vessel size on creation of hepatic radiofrequency lesions in pigs: Assessment of the “Heat sink effect”. American Journal of Roentgenology, 178: 47-51, 2002. Crossref

Chang, C. K., Hendy, M., Smith, M., Recht, M., and Welling, R., Radiofrequency ablation of the porcine liver with complete hepatic vascular occlusion. Annals of surgical oncology, 9: 594-598, 2002. Crossref

Abraham, J.P., and Sparrow, E.M., A thermal-ablation bioheat model including liquid-to-vapor phase change, pressure- and necrosis-dependent perfusion, and moisture-dependent properties. Int J Heat Mass Transfer, 50: 2537–44, 2007. Crossref

Kolios, M.C., Sherar, M.D., and Hunt, J.W., Large blood vessel cooling in heated tissues: a numerical study. Phys. Med. Biol., 40: 477-494, 1995. Crossref

Berjano, E.J., Theoretical modelling for radiofrequency ablation: state-of-the-art and challenges for the future. Biomedical engineering online, 5:24, 2006.

Burdio, F., Guemes, A., Burdio, J.M., et al., Bipolar saline-enhanced electrode for radiofrequency ablation: results of experimental study of in vivo porcine liver. Radiology 229:447-456, 2003. Crossref

Lee, J.M., Han, J.K., Kim, S.H., Lee, J.Y., Kim, D.J., Lee, M.W., Cho, G.G., Han, C.J., and Choi, B.I., Saline-enhanced hepatic radiofrequency ablation using a perfused-cooled electrode: comparison of dual probe bipolar mode with monopolar and single probe bipolar modes,Korean J Radiol. 5(2):121-7,2004. Crossref

Haemmerich, D., Staelin, S.T., Tungjitkusolmun, S., Lee, F.T., Mahvi, D.M., Webster, J.G., Hepatic bipolar radiofrequency ablation between separated multiprong electrodes. IEEE Trans BioMed Eng, 48:1145-1152, 2001

Oregon, Link, (Retrieved 17th January, 2016)

Walker, D. C., Brown, B. H., Rose, D. R. and Smallwood, R. H. Modelling the electrical impedivity of normal and premalignant cervical tissue. Electronics Letters, 36 (19): 1603-1604, 2000. Crossref

MR Usikalu, M Aweda, J Wan, N Ding (2010). Genotoxic effects of low 2.45 GHz microwave radiation exposures on Sprague Dawley rats, International Journal of Genetics and Molecular Biology 2 (9), 189-197

MR Usikalu, SO Rotimi, AE Oguegbu, (2012). Effect of exposure of 900 MHz radiofrequency radiation on rat brain, European Journal of Experimental Biology 2 (6), 2499-2504

MR Usikalu, OO Obembe, ML Akinyemi, J Zhu. (2013). Short-duration exposure to 2.45 GHz microwave radiation induces DNA damage in Sprague Dawley rat’s reproductive systems, African Journal of Biotechnology 12 (2):15. Crossref




DOI: http://dx.doi.org/10.21152/1750-9548.12.3.257

Copyright (c) 2018 M Emetere, B Muhammad, E Bolujo

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